Author

Xubin Li

The University of Texas MD Anderson Cancer CenterORCID 0000-0003-1727-9215Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Ahyun Choi· 1 shared Alan B CooperiD· 1 shared Ali ElSheikh· 1 shared Bing LiuiD· 1 shared Chaomei Shi· 1 shared Chizitara Okwuchi· 1 shared Cuong Minh Quoc LeiD· 1 shared Dinesh S. BangariiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

Ahyun Choi

Mutual co-authors in cluster

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintOct 21, 2026

Harnessing the PRDM1-PGC1A axis to enhance CAR T cell efficacy

Sidney YY Wang, Xiufen Chen, Xubin Li…·Jutin Kline

This study identifies the PRDM1-PGC1A axis as a key regulator of CAR T cell function, showing that inhibiting PRDM1 or activating PGC1A improves CAR T cell efficacy in multiple tumor models.

DOI 10.64898/2026.10.15.759372

humanstatistical model

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ImmunologybioRxivPreprintAug 28, 2023

CD8 T-cell dysfunction is linked with CAR T-cell failure and can be mitigated by a non-alpha IL-2 agonist, pegenzileukin

Patrick Kevin Reville, Irtiza N. Sheikh, Ahyun Choi…·Michael Green

The paper identifies dysfunctional CD8 CAR T-cells in rrLBCL tumors and shows that pegenzileukin mitigates this dysfunction, improving CAR T-cell responses.

1 citation

humanscRNA-seq

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