Melanie D. Ohi

This study uses cryo-EM to capture intermediate states of maltooligosaccharide transport by the SusCD complex in Bacteroides, revealing its heterodimeric structure and binding mechanisms.

ResiRuler quantifies and visualizes residue-residue distances and structural changes across protein ensembles to identify conformational differences.

This study investigates how sodium and lithium regulate the fluoride exporter FEX, revealing structural and functional differences in their effects on channel activity and fluoride tolerance in yeast.

This study identifies how caveolin-1's hydrophobic residue patterning drives membrane bending through structural and computational analyses.

This study identifies the molecular mechanism of sodium-dependent fluoride export by FEX proteins using electrophysiology, cryo-EM, and simulations.

This study determines the structural plasticity of HIV-1 RRE stem-loop II and shows how it modulates Rev binding and nuclear export of viral RNA.

The paper presents the structure of yeast CPT1 in multiple substrate-bound states to elucidate the mechanism of phospholipid synthesis and selectivity.

This study shows that lpdA regulates iron-mediated motility in UPEC, which impacts virulence under iron-limited conditions.