Chiara Francavilla

The paper identifies STRIPAK as a novel co-assembly factor of Rabex5-Rabaptin5, showing subunit-specific effects on early endosome formation and EGFR transport.

InstaNovo-P improves phosphorylated peptide detection and site localization in phosphoproteomics by using a transformer-based model fine-tuned on phosphoproteomics data.

The paper investigates dermokine's role in keratinocyte adhesion through multi-omics analysis, showing that dermokine loss increases p120 phosphorylation and reduces cell-cell adhesion.

The paper identifies osteomodulin as a promoter of breast cancer bone metastasis through CDK1 activation using proteomics and phosphoproteomics analysis of patient-derived tumors.

The paper quantifies kinase activity dynamics in response to FGF ligands and uses dynamic modeling to reveal pathway regulation and novel kinase involvement.

SubcellulaRVis visualizes subcellular compartment enrichment of gene lists using a eukaryotic cell diagram, improving interpretation of protein localization from enrichment analyses.

The paper introduces a method to infer functions of phosphorylated sites using a heterogeneous multilayer network and validates it on phosphoproteomics data.