Robert B. Clarke

This study identifies ARID1A's role in regulating FOXA1 and AP-2 transcription factors in lobular breast cancer, revealing a distinct regulatory network and potential implications for metastasis.

This paper develops an in vitro model to study metastatic niche priming and interactions between primary and metastatic sites in breast cancer.

This study uses super-resolution microscopy to analyze HER2 nanoclustering in breast cancer tissues, revealing grade-dependent patterns and reclassifying samples based on nanoscale features.

DIANNeR improves detection of GR interactomes in normal tissues by integrating DIA, ion mobility, and library-free analysis, revealing context-specific networks and previously undetected interactions.

This study shows that HES1 protein oscillations are necessary for ER+ breast cancer cells to re-enter the cell cycle, and disrupting these oscillations prevents reactivation of dormant cells.

The paper identifies PR-expressing basal cells and PR-primed progenitors, redefining mammary epithelial hierarchy and challenging existing models of breast biology and cancer.

This study shows MYBL2 maintains stemness and promotes theta-mediated end joining in TNBC, and identifies Pol{theta}/ATR inhibition as a therapeutic strategy.

The paper identifies osteomodulin as a promoter of breast cancer bone metastasis through CDK1 activation using proteomics and phosphoproteomics analysis of patient-derived tumors.