Author

Purvi R. Patel

Vanderbilt UniversityORCID 0000-0003-1914-3004Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Genetics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Alexei ChemiakineiD· 1 shared Andrea C. FlorianiD· 1 shared Brian C. GriebiD· 1 shared Brianna N. SmithiD· 1 shared Camden Jones· 1 shared Chloe KimiD· 1 shared Colton J. TreadwayiD· 1 shared Elizabeth M. Reynolds· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperGenetics

Alexei ChemiakineORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cancer BiologyJournal of Extracellular BiologyPeer-reviewedMay 1, 2026

Mammary Fibroblasts Secrete Damage Associated Molecular Patterns through Extracellular Vesicles in Response to Ionizing Radiation

Greg Berumen Sánchez, Purvi R. Patel, Preston Gomez-Crase…·Marjan Rafat

This study shows that mammary fibroblasts release DAMPs via extracellular vesicles after ionizing radiation, with Rab27a regulating this process.

2 citations

mouseproteomics

𝕏 PostBluesky

Cancer BiologyeLifePeer-reviewedOct 17, 2023

Ribosome subunit attrition and activation of the p53-MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition

Gregory Caleb Howard, Jing Wang, Kristie Lindsay Rose…·William P. Tansey

This study identifies that WDR5 WIN site inhibitors suppress ribosome protein gene transcription, induce nucleolar stress, and activate p53 in MLL-rearranged cancer cells, revealing a novel ribosome-directed anti-cancer mechanism.

22 citations

humanbulk RNA-seq

𝕏 PostBluesky

GeneticsThe EMBO JournalPeer-reviewedApr 18, 2023

Dosage sensitivity in Pumilio1-related phenotypes reflects distinct disease mechanisms

Salvatore Botta, Nicola de Prisco, Alexei Chemiakine…·Vincenzo Alessandro Gennarino

The paper investigates how different PUM1 mutations lead to distinct phenotypes by analyzing PUM1 interactomes and showing that dosage sensitivity involves non-linear mechanisms.

12 citations

mouseproteomics

𝕏 PostBluesky