Author

Katherine E. Squires

Emory UniversityORCID 0000-0003-1925-2921Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:protein design· 1

Frequent Co-Authors

John R. HepleriD· 2 shared Carolina Montañez‐MirandaiD· 1 shared Christopher D. SchareriD· 1 shared Clara E. Magyar· 1 shared Daniel J. LustbergiD· 1 shared David R. Emlet· 1 shared David WeinshenkeriD· 1 shared Eric A. OrtlundiD· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMolecular Biology

John R. HeplerORCID

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2 papers

Recent·Most cited

Molecular BiologyJournal of Biological ChemistryPeer-reviewedNov 5, 2020

Human genetic variants disrupt RGS14 nuclear shuttling and regulation of LTP in hippocampal neurons

Katherine E. Squires, Kyle J. Gerber, Matthew C. Tillman…·John R. Hepler

The paper identifies genetic variants in RGS14 that disrupt nuclear shuttling and impair LTP regulation in hippocampal neurons, with variant LR causing nuclear accumulation and loss of function.

16 citations

humanmouse

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Pharmacology & ToxicologybioRxivPreprintFeb 5, 2019

Genetic variants disrupt human RGS14 binding to NHERF1 and regulation of NPT2A-mediated phosphate transport

Peter A. Friedman, Tatyana Mamonova, Clara E. Magyar…·John R. Hepler

This study identifies how genetic variants in RGS14 affect its interaction with NHERF1 and regulation of phosphate transport, showing some variants disrupt binding while others maintain function.

DOI 10.1101/540781

humanproteomics

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