Ido Caspy

This study determines the structure of a large S-layer protein from Pyrobaculum arsenaticum using cryo-EM and AlphaFold, revealing its unique multidomain architecture and evolutionary conservation.

This study shows mechanical compression induces tissue-like multicellularity in haloarchaea, forming structures with distinct molecular and mechanical features similar to eukaryotic tissues.

The paper shows that the S-layer in Sulfolobus acidocaldarius aids cell division by reshaping the cytokinetic furrow through its flexible self-assembly, enhancing ESCRT-III-dependent division under mechanical stress.

This study reports the 3.2 Å resolution structure of the Pseudomonas aeruginosa PAO1 Type IV pilus using cryo-EM, revealing its architecture and potential functional roles.