Terry Smith

This study compares lipidomic profiles of Trypanosoma congolense and Trypanosoma brucei to understand their metabolic differences and implications for in vitro culture and therapy development.

This study defines the molecular architecture of Influenza A virions using structural and compositional approaches, revealing unique features of filamentous virions.

This study identifies TslM as a novel reverse domain arrangement substrate of the Staphylococcus aureus type VII secretion system, revealing its lipase activity and secretion mechanism.

This study shows that disrupting the hexosamine biosynthetic pathway in Plasmodium falciparum blocks GPI production, arrests parasite growth, and prevents egress from host cells.

The paper reports the cryo-EM structure of the RP4 conjugation pilus, revealing it is functional without phospholipid modification, challenging previous assumptions about pilus biogenesis.

This study investigates the activity and essentiality of the putative Delta6-desaturase in Trypanosoma brucei, showing its role in producing specific polyunsaturated fatty acids and influencing lipid composition and morphology during life cycle transitions.

The paper presents the cryo-EM structure of the R388 plasmid conjugative pilus, revealing a unique pilin/phospholipid complex and structural differences from other conjugative pili.

This study investigates how copper and copper oxide surfaces inactivate SARS-CoV-2, showing that copper ion dissolution and complexation with biomolecules in the carrier solution are key factors.

The paper identifies a new class of T7SS effector, TslA, with a reverse domain arrangement and describes its secretion mechanism and functional properties.