Caio César Barbosa Bomfim

This study uses dual human lung models to evaluate anti-tuberculosis drugs and host-directed therapies, revealing compartment-specific efficacy and immune responses.

This study shows that cannabidiol inhibits HIV-1 transmission by targeting multiple immune cells and blocking viral infection and transfer in mucosal tissues.

This study shows CD39 prevents necrotic lung lesions in tuberculosis by inhibiting P2RX7-mediated macrophage death and inflammation.

The paper identifies PP1 and PP2A phosphatases as regulators of NLRP1 inflammasome activation, showing that environmental toxins and viral infections trigger this pathway via TAK1 and p38 kinases.

This study identifies PU.1 as a key transcription factor regulating epigenetic responses to Mtb, showing its role in supporting infection and potential as a therapeutic target.