Author

Axel Pahl

Fraunhofer Institute for Translational Medicine and PharmacologyORCID 0000-0003-2068-7543Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Assay:imaging· 2 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Annina Burhop· 1 shared Bob van de WateriD· 1 shared Carina Seitz· 1 shared Daya Agne· 1 shared Gerhard Franz EckeriD· 1 shared Giulia CallegaroiD· 1 shared Herbert WaldmanniD· 1 shared Hugo W van KesseliD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCell Biology

Annina Burhop

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2 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintOct 20, 2026

Cell Painting PLUS expands morphological profiling to enhance mechanistic understanding of compounds

Marlene Wedler, José M. Muiño, Axel Pahl…·Shu Liu

The paper evaluates Cell Painting (CP) and Cell Painting PLUS (CPP) for predicting compound mechanisms of action, finding CPP better resolves off-target effects and improves MoA prediction for lysosome-related compounds.

DOI 10.64898/2026.10.14.757934

humanimaging

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Cell BiologyJournal of Medicinal ChemistryPeer-reviewedJul 17, 2024

Detection of a Mitochondrial Stress Phenotype using the Cell Painting Assay

Soheila Rezaei Adariani, Daya Agne, Sandra Koska…·Slava Ziegler

The paper shows that the Cell Painting assay can detect mitochondrial stress and predict mitochondrial toxicity in small molecules.

16 citations

imagingexperimental assay

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