Author

Bakar A. Hassan

National Institutes of HealthORCID 0000-0003-2079-6387Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:chromatin & epigenetic regulation· 2 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

Aayatti Mallick GuptaiD· 1 shared Achim A WerneriD· 1 shared Alex Gorman· 1 shared Athena Lam· 1 shared Benjamin TerrieriD· 1 shared Bernice Y. KwongiD· 1 shared David B. BeckiD· 1 shared Erika Anne TayloriD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperEvolutionary Biology

Aayatti Mallick GuptaORCID

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2 papers

Recent·Most cited

Evolutionary BiologyProtein SciencePeer-reviewedJan 20, 2026

Structural Adaptations of HepI Enzymes in Proteobacteria: Insights into Evolutionary Resilience and Functional Dynamics

Aayatti Mallick Gupta, Hamza Habib, Bakar A. Hassan…·Erika Anne Taylor

This study identifies sequence motifs in HepI enzymes that correlate with LPS structural features and reveals structural adaptations linked to evolutionary resilience and functional versatility in proteobacteria.

2 citations

bacteria (other)protein structure

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BiochemistryThe EMBO JournalPeer-reviewedFeb 15, 2024

Shared and Distinct Mechanisms of UBA1 Inactivation Across Different Diseases

Jason C. Collins, Samuel J. Magaziner, Maya English…·Achim A Werner

This study identifies shared and distinct mechanisms of UBA1 inactivation in VEXAS syndrome and related diseases, revealing how different mutations affect ubiquitin transfer to E2 enzymes.

48 citationstop 2%

humanproteomics

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