Author

Nidheesh Thadathil

University of Oklahoma Health Sciences CenterORCID 0000-0003-2168-8337Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Arlan G RichardsoniD· 2 shared Evan H. NicklasiD· 2 shared Sabira MohammediD· 2 shared Sathyaseelan S. DeepaiD· 2 shared Albert Tran· 1 shared Dawei WangiD· 1 shared Hoang Van M. NguyeniD· 1 shared Jacob W. FarriesteriD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiochemistry

Arlan G RichardsonORCID

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2 papers

Recent·Most cited

BiochemistryInternational Journal of Molecular SciencesPeer-reviewedFeb 28, 2024

Non-Necroptotic Roles of MLKL in Diet-Induced Obesity, Liver Pathology, and Insulin Sensitivity: Insights from a High Fat, High Fructose, High Cholesterol Diet Mouse Model

Phoebe Ohene-Marfo, Hoang Van M. Nguyen, Sabira Mohammed…·Sathyaseelan S. Deepa

This study investigates MLKL's non-necroptotic roles in diet-induced obesity and liver disease using a HFHFrHC mouse model, finding dose-dependent effects on inflammation and metabolic parameters.

12 citations

mousebulk RNA-seq

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NeuroscienceGeroSciencePeer-reviewedSep 13, 2021

Necroptosis increases with age in the brain and contributes to age-related neuroinflammation

Nidheesh Thadathil, Evan H. Nicklas, Sabira Mohammed…·Sathyaseelan S. Deepa

This study shows that necroptosis increases with age in the brain and contributes to age-related neuroinflammation in mice.

71 citations

mouseprotein structure

𝕏 PostBluesky