Aykut Erbaş

This study uses a polymer-physics model to show how lamin binding parameters control nuclear lamina structure and mechanopathology.

The paper investigates how lamina-associated domains (LADs) act as size-selective steric barriers to limit protein access to the nuclear periphery, providing a biophysical mechanism for gene regulation.

The paper investigates how peripheral heterochromatin tethering influences nuclear mechanical response through simulations and experiments.

This study models lamin aggregation and dissociation in progeria using polymer chains to show how molecular interactions and concentration affect nuclear lamina structure and stability.

This study uses a polymer model to show that chromatin phase separation and nuclear shape fluctuations are correlated, with heterochromatin levels and interactions affecting nuclear stability.

The paper models peripheral chromatin as a flexible polymer chain using de Gennes' self-similar carpet theory to explain two experimental observations about chromatin density and molecular exclusion near the nuclear envelope.