Brigid V. Troan

The paper analyzes immune-cancer tradeoffs across mammals, finding a negative correlation between cancer and trauma mortality, mediated by platelet size and trophic level.

This paper demonstrates that MM3122, a host cell serine protease inhibitor, effectively inhibits SARS-CoV-2 replication and reduces disease severity in mice, both prophylactically and therapeutically.

This study tests adaptive therapy protocols using gemcitabine and capecitabine on a mouse model of endocrine-resistant breast cancer, finding improved survival with adaptive strategies over high-dose combination therapy.