Author

Laura A. Jamrog

Centre National de la Recherche ScientifiqueORCID 0000-0003-2288-0806Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Bastien GerbyiD· 1 shared Camille HamelleiD· 1 shared Christine DidieriD· 1 shared Cyril BroccardoiD· 1 shared Eric Delabesse· 1 shared Esmaa Sellam· 1 shared Laëtitia LargeaudiD· 1 shared Manon BayetiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Bastien GerbyORCID

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1 paper

Recent·Most cited

Cell BiologyEJC Paediatric OncologyPeer-reviewedDec 1, 2023

Loss of HSC stemness identity is associated with exhaustion and hyporesponsiveness in GATA2 deficiency syndrome

Laëtitia Largeaud, Vincent Fregona, Laura A. Jamrog…·Cyril Broccardo

This study shows that GATA2 mutations impair HSC function by reducing self-renewal and responsiveness to inflammation, leading to immunodeficiency and myeloid malignancies.

1 citation

mousebulk RNA-seq

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