Cell BiologyArteriosclerosis Thrombosis and Vascular BiologyPeer-reviewed
FOXC1 and FOXC2 maintain mitral valve endothelial cell junctions, extracellular matrix, and lymphatic vessels to prevent myxomatous degeneration
Can Tan, Zhi‐Dong Ge, Shreya Kurup…·Tsutomu Kume
This study shows that Foxc1 and Foxc2 are essential for maintaining mitral valve structure by preserving endothelial cell junctions, extracellular matrix, and lymphatic vessels, preventing myxomatous degeneration.
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