Paola Drapkin Vermeer

The paper shows that cholesterol deficiency leads to autophagy-dependent secretion of extracellular vesicles, with potential pathological implications in cholesterol-related diseases.

This study shows that nociceptor neurons promote immunosuppression in tumors by increasing MDSC infiltration and CD8+ T cell exhaustion through IL-6 and sEVs.

This study shows tumor-infiltrating nerves alter brain circuits and behavior in a male mouse model of head-and-neck cancer by changing neural activity and behavior.

This study identifies Cancer-sEVs as mediators of cancer pain by inducing neuronal hypersensitivity and translation, with potential therapeutic targets identified.