Structural Analysis and Docking Studies of FK506-Binding Protein 1A
This study presents the crystal structure of FKBP1A at 1.05 Å resolution and performs docking studies to explore potential drug repurposing opportunities.
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Koç UniversityORCID 0000-0003-2388-5297Unclaimed ORCID profile · follow to get notified of new preprints
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This study presents the crystal structure of FKBP1A at 1.05 Å resolution and performs docking studies to explore potential drug repurposing opportunities.
İlkin Yapici, E. Han Dao, Shun Yokoi…·Hasan DeMirci
This study uses 4D crystallography to capture transient dynamics of IF1 binding to the 30S ribosomal subunit, revealing allostery and interactions during translation initiation.
Ömür Güven, Halil I. Ciftci, Hiroshi Tateishi…·Hasan DeMi̇rci̇
The paper presents the structure of TRAF6 N-terminal domain at 2.6 Å resolution, providing insights into its domain organization and zinc-binding, which are critical for its function and therapeutic targeting.
Ömür Güven, Mehmet Gül, Esra Beyarslan Ayan…·Hasan DeMi̇rci̇
This study demonstrates a high-throughput drug screening protocol using serial femtosecond X-ray crystallography for SARS-CoV-2 main protease, achieving 120 images/second with a new detector.