Joshua D. Frenster

The paper identifies a developmentally regulated long-range enhancer-promoter contact that is critical for SOX2 expression and neuroectodermal differentiation in human neural development.

This study compares the effects of homemade and commercial N2B27 media on mouse gastruloid development, finding differences in timing, cell number, and gene expression patterns.

This study uses mosaic gastruloids to show that cell competition in mammalian embryos is restricted to a specific developmental window and depends on signaling pathways like Wnt and BMP.

This study identifies CD97 as a targetable vulnerability in glioblastoma through its role in tumor metabolism and signaling, supported by transcriptomic, proteomic, and functional analyses.