Author

Max A. K. Rätze

University Medical Center UtrechtORCID 0000-0003-2466-0719Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Christina H. J. VeltmaniD· 1 shared Isaäc J. NijmaniD· 1 shared Lotte N.F.L. Enserink· 1 shared Matthias ChristgeniD· 1 shared Noboru IshiyamaiD· 1 shared P. J. van DiestiD· 1 shared Patrick W.B. DerkseniD· 1 shared R. R. BernardsiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperCancer Biology

Christina H. J. VeltmanORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintJul 4, 2023

Somatic mutation of Afadin leads to anchorage independent survival and metastatic growth of breast cancer through alpha E-catenin dependent destabilization of the adherens junction

Max A. K. Rätze, Lotte N.F.L. Enserink, Noboru Ishiyama…·Patrick W.B. Derksen

This study identifies a somatic Afadin mutation that destabilizes adherens junctions and promotes metastatic growth in breast cancer by disrupting E-catenin binding.

1 citation

humanwhole-genome sequencing

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