Petra I. Knaus

The paper evaluates cofolding models for kinases and GPCRs, finding that ligand accuracy often decouples from overall conformational state recovery, with implications for drug design.

This study identifies TGFβ-induced SMAD1/5 activation as critical for transient EMT in trophoblasts, linking it to placental development and preeclampsia.

This study shows that gut microbial metabolite imidazole propionate impairs endothelial function and promotes atherosclerosis in both human and animal models.

This study identifies SMAD/FOXO1 complexes that mediate EndoMT in response to atheroprone flow, showing their role in atherosclerosis and suggesting targeting this interaction could reduce disease progression.

This study shows Septin9 regulates myoblast differentiation by reorganizing cytoskeletal structures during early myogenesis.

This study identifies Osr1 as essential for FAPs to support muscle regeneration by regulating communication with MuSCs and macrophages, and its loss leads to impaired regeneration and fibrosis.