Paras Anand

This study shows that lipid droplet accumulation promotes NLRP3 inflammasome activation through glutamine-dependent metabolic reprogramming in macrophages.

This study shows that TLR4 signalling selectively regulates lipid transport proteins in human macrophages but not in mouse macrophages, highlighting species-specific differences in immune-lipid interactions.

This study shows that fatty acid synthesis promotes NLRP3 inflammasome activation through palmitoylation of NLRP3, with no effect on AIM2 inflammasome activation.