Juliane Liepe

PMGen improves peptide-MHC structure prediction and enables structure-guided peptide design, achieving high accuracy and enhancing ML model performance.

The paper identifies Mos-MAPK targets in starfish oocytes using phosphoproteomics, revealing roles in mRNA polyadenylation and cytoskeletal regulation during meiosis.

The paper introduces chemical crosslinking with mass spectrometry and a new search engine, NuXL, to identify nucleic acid-protein crosslinks at amino acid resolution, enhancing structural analysis.

The paper uses single-cell tracking to show that HSCs from infected mice exhibit heterogeneous movement patterns compared to controls, with increased persistence possibly aiding survival in altered niche environments.