Jorge Hernández‐García

This study shows that MpARF2 forms nanoclusters that enable high-affinity, switch-like, and sequence-specific DNA binding, distinct from monomeric or condensate-based mechanisms.

The paper identifies a biochemical mechanism by which the MpARF1 transcription factor activates gene expression through subnuclear clustering and Mediator complex recruitment, revealing an evolutionary innovation in auxin response.

PharaohFUN is a web tool for evolutionary and functional analysis of protein sequences in photosynthetic eukaryotes, using orthology relationships to unify analyses across species.

This study shows that plants can grow under limited water without compromising stress tolerance, but continuous cell division under stress causes DNA damage and cell death.

The paper identifies a minimal region responsible for ARF degradation in Marchantia polymorpha, showing it is critical for development and auxin response, and suggests ARF instability predates the auxin response system.

The paper investigates auxin and tryptophan responses in the alga Penium margaritaceum, finding shared physiological and transcriptomic responses between auxin and tryptophan.

The paper shows that the ARF-DNA interface is ultra-conserved across plant lineages, explaining the evolutionary stability of auxin signaling.

This study investigates the evolutionary origins and functional diversification of Auxin Response Factors (ARFs) through in silico and in vivo analyses, revealing their shared origin and evolutionary trajectory.

Metapredict V3 predicts intrinsically disordered regions across 20,000 proteomes to assess disorder prevalence across life kingdoms.

This paper identifies DELLA proteins as co-activators that recruit the Mediator subunit MED15 to facilitate transcription in land plants, showing conservation from Arabidopsis to liverworts.