Author

Abhishek Bharadwaj Sharma

Luxembourg Institute of HealthORCID 0000-0003-2554-1025Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Alexandra MihuțiD· 1 shared Andrew James BowmaniD· 1 shared Anna Georgina KopasziD· 1 shared Barbara KlinkiD· 1 shared Christel C. Herold-Mende· 1 shared Eric Van Dyck· 1 shared Eva Pinto JuradoiD· 1 shared Gyula TiminszkyiD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

Alexandra MihuțORCID

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2 papers

Recent·Most cited

Cell BiologyNucleic Acids ResearchPeer-reviewedJun 3, 2024

The loss of DNA polymerase epsilon accessory subunits POLE3-POLE4 leads to BRCA1-independent PARP inhibitor sensitivity

Hasan Mamar, Roberta Fajka‐Boja, Mónika Mórocz…·Gyula Timinszky

This study shows that loss of POLE4 leads to PARP inhibitor sensitivity independent of BRCA1, through replication stress and DNA-PK signaling changes.

13 citations

humanDNA methylation

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Molecular BiologybioRxivPreprintApr 10, 2020

XAB2 prevents abortive recombinational repair of replication-associated DNA double-strand breaks and its loss is synthetic lethal with RAD52 inhibition

Abhishek Bharadwaj Sharma, Hélène Erasimus, Lia Pinto…·Eric Van Dyck

DOI 10.1101/2020.04.10.035410

humanDNA methylation

𝕏 PostBluesky