Saaz Sakrikar

This study shows that high spontaneous aneuploidy rates, not drug-induced mutations, drive fluconazole resistance in yeast through chromosome duplication at ERG11.

The paper identifies TroR as the primary regulator of iron homeostasis in Haloferax volcanii and shows it represses iron uptake and induces storage under iron sufficiency.

This paper compares rRNA removal methods for RNA-seq in halophilic archaea, finding that probe-specificity is critical for effective rRNA depletion and improved transcript detection.

This study identifies HpyA, an archaeal histone-like protein, as a transcriptional regulator that modulates gene expression in response to salt stress in Halobacterium salinarum.