Thomas Walz

This study shows that CgMscS from Corynebacterium glutamicum opens at higher membrane tension than EcMscS and uses a distinct gating mechanism not based on the 'lipids-move-first' model.

This study characterizes the structure and function of MscM, revealing that its cytoplasmic domain mediates channel gating through conformational changes, differing from other MscS-like channels.

This study presents cryo-EM structures of the human TCR-CD3 complex in its resting and ligand-bound states, revealing conformational changes and the importance of native lipid environments.