Author
National Heart, Lung, and Blood InstituteORCID 0000-0003-2621-7307Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Stephanie L. Sarbanes, Jakub Žiak, Alex L. Kolodkin, Antonina Roll‐Mecak
This study shows TTC5 regulates tubulin autoregulation in neurons, affecting morphology and migration, and links TTC5 dysfunction to neurodevelopmental disorders.
Stella A.C. Whittaker, Elizabeth D. McKenna, Stephanie L. Sarbanes…·Antonina Roll‐Mecak
The paper introduces a high-throughput 3D culture system for imaging axonal processes in human iPSC-derived neurons, enabling efficient study of microtubule dynamics and cargo transport.
Kengo Nishi, Sufi Raja, An Pham…·Christoph F. Schmidt
The paper measures microtubule mechanics in living cells using motor-generated forces and shows that polyglutamylation increases microtubule stiffness.
Jeffrey O. Spector, Jiayi Chen, Ewa Szczęsna, Antonina Roll‐Mecak
The paper describes a modified multi-color TIRF microscope that enables simultaneous IRM and single molecule TIRF imaging of microtubules and EB1 proteins.
Steven W. Cummings, Yan Li, Jeffrey O. Spector…·Antonina Roll‐Mecak
This study identifies substrate preferences and regulatory mechanisms of TTLL glycylases, showing how tubulin glutamylation and polyglycylation influence TTLL10 activity and microtubule modification.
Elena A. Zehr, Antonina Roll‐Mecak
The paper reports cryo-EM structures of human α1B/βI+βIVb microtubules in GDP and GTP-like states, revealing isoform-specific sequence variations affecting polymerization interfaces and microtubule dynamics.