Teun Bousema

The paper identifies human antibodies against a mosquito salivary protein, SG1L3, that binds to Plasmodium falciparum sporozoites but does not block infection.

This paper develops a joint Bayesian model to analyze P. vivax parasite density, gametocyte density, and mosquito infectivity, showing gametocyte density has the strongest association with infectivity.

The paper measures sporozoite expulsion in mosquitoes during repeated feeding and finds similar sporozoite inoculation intensity in subsequent attempts.

This study uses deep learning to analyze mosquito behavior changes after infection, finding species-specific effects that could impact disease transmission.

This study uses the SpitGrid platform to measure sporozoite inoculum dynamics in Plasmodium-infected mosquitoes, revealing temporal patterns and behavioral factors influencing transmission.

The paper identifies Wnt signaling as critical for Plasmodium falciparum liver schizont maturation by using a novel medium to maintain hepatocyte functionality and analyze host-parasite interactions.

This study identifies Pfs230 Domain 12 as a potent malaria transmission-blocking vaccine candidate that induces antibodies reducing parasite transmission to mosquitoes.

This paper models recombination's impact on multi-drug resistance evolution in malaria, showing that most recombinant genotypes arise from multi-clonal infections and that ACT strategies reduce treatment failures and delay resistance.

The paper investigates mosquito biting preferences among festivalgoers, finding that beer consumption, shared sleeping, and lack of sunscreen use increase attractiveness.

The paper develops an in vitro and in vivo platform for testing malaria transmission-blocking drugs using engineered Plasmodium falciparum gametocytes and humanized mice.

In Tororo, Uganda, An. funestus tolerated clothianidin-sprayed walls better than An. gambiae yet was killed on pirimiphos-methyl walls up to 7 months post-spray, implicating it in the malaria resurgence.

This study shows that surface remodelling in Plasmodium falciparum gametocytes helps evade immune detection and facilitates transmission by controlling their sequestration and release into the bloodstream.

This study compares gametocyte production and transmission fitness of ART-sensitive and ART-resistant P. falciparum isolates across multiple mosquito species.

The paper determines the structure of the Pfs230:Pfs48/45 complex bound to transmission-blocking antibodies, revealing molecular interactions and epitopes that inform vaccine development.

The paper identifies human antibodies targeting Plasmodium falciparum sexual stages, revealing cross-stage recognition of glutamate-rich repeats through a novel method.

This study shows that AlbuMAX supplemented media increases the production of transmission-competent Plasmodium falciparum gametocytes compared to serum.

The paper quantifies sporozoite expulsion from Anopheles mosquitoes infected with P. falciparum gametocytes, finding that infection burden correlates with sporozoite expulsion.

This study compares two mosquito rearing methods for Anopheles stephensi to improve homogeneity and parasite receptiveness for malaria research.