Erdem D. Tabdanov

This study identifies dynein-microtubule forces as essential for nuclear translocation and transmigration in T cells, showing dynein's dual role as a motor and force-transmission element.

This paper demonstrates that UR214-9 disrupts septin hetero-octamerization, leading to aberrant structures and impairing cancer cell functions.

This study identifies GDF-15 as a mechanosensing-regulated driver of melanoma pathogenesis, linking mechanical stress, vascular disorganization, and immune suppression.

This study identifies ACTN4 as a non-muscle α-actinin in cardiac sarcomeres, showing it regulates contractility, hypertrophy, and heart remodeling without disease hallmarks.

This study investigates the impaired mechanobiological response of female ACLs to mechanical loading and finds fewer differentially expressed genes and enriched mechanotransduction pathways in females compared to males.

The paper models immune cell migration by integrating nuclear piston, uropod, and microenvironment mechanics to show how they synergize for efficient movement through dense tissues.

This study compares the biological response of allograft and autograft ACL reconstructions to cyclic loading and finds no difference in remodeling or immune cell markers.

This study uses AD organoids to identify dynamic neuroinflammatory profiles and their impact on neuronal health and microglial function.

This study shows that septins regulate T cell migration modes by switching between amoeboid and mesenchymal movement, with mesenchymal migration relying on microtubules and dynein motors.