Author

Andrea Orsi

IRCCS Ospedale San RaffaeleORCID 0000-0003-2839-1640Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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2017-2024 · peak 1/yr

10 top collaborators · 39 mutual co-author links

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2 shared papersCell Biology

Eelco van AnkenORCID

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2 papers

Cell BiologyLife Science AlliancePeer-reviewedJun 17, 2024

This study shows that IRE1α requires multiple dimers to undergo cross-phosphorylation and activate its RNase activity during ER stress.

4 citations

Cell BiologybioRxivPreprintMay 5, 2017

The paper shows the UPR transitions from pro-survival to pro-death when ER expansion is excessive, using HeLa cells and genetic manipulations.

DOI 10.1101/134726