Alison B. Moe

The paper investigates how Rho and Cdc42 signaling zones form and polarize during cell repair in Xenopus oocytes, revealing a self-organized mechanism involving protein recruitment at signaling compartment overlaps.

This study shows that CB2R on microglia drives neuroinflammation in GVHD by promoting T cell activation and neuronal death, and that targeting CB2R reduces inflammation without worsening systemic GVHD.