Author

Florian Pernin

Montreal Neurological Institute and HospitalORCID 0000-0003-2877-3673Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Assay:ATAC-seq· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Alexandre PratiD· 2 shared Jack Perry AnteliD· 2 shared Stéphanie ZandeeiD· 2 shared Camilo Faust AkliD· 1 shared Chun‐Cheih ChaoiD· 1 shared Federico GiovannoniiD· 1 shared Francisco Javier QuintanaiD· 1 shared Gavin PiesteriD· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersImmunology

Alexandre PratORCID

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2 papers

Recent·Most cited

ImmunologyNaturePeer-reviewedMar 20, 2024

Disease-associated astrocyte epigenetic memory promotes CNS pathology

Hong‐Gyun Lee, Joseph M. Rone, Zhaorong Li…·Francisco Javier Quintana

This study identifies an epigenetically controlled memory astrocyte subset that exacerbates CNS pathology in EAE and MS by promoting pro-inflammatory responses.

139 citationstop 1%

mousescRNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintNov 5, 2019

RNA-binding protein altered expression and mislocalization in multiple sclerosis

Katsuhisa Masaki, Yoshifumi Sonobe, Ghanashyam D. Ghadge…·Raymond P. Roos

The paper investigates altered expression and mislocalization of RNA-binding proteins TDP-43 and PTB in multiple sclerosis lesions and cultured oligodendrocytes, linking them to demyelination and neurodegeneration.

DOI 10.1101/829457

humanprotein sequence

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