Author
University Medical Center UtrechtORCID 0000-0003-2911-6018Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Susanna Plugge, H. Ma, Jelte van der Vaart…·Madelon M. Maurice
This study shows that LKB1 loss in intestinal cells leads to a pre-malignant state linked to serrated colorectal cancer, which is amplified by loss-of-heterozygosity.
W. R. Vallentgoed, Youri Hoogstrate, Karin A. van Garderen…·Pim J. French
The paper analyzes multi-omics data from IDH-mutant astrocytomas to identify molecular markers of malignant progression linked to cell cycling and DNA methylation changes.
Paul Roepman, Ewart de Bruijn, Stef van Lieshout…·Edwin P. J. G. Cuppen
This study validates whole genome sequencing as a reliable single assay for detecting various cancer mutations with high sensitivity and precision.