Author

C. Jamieson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1

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Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Approach:genetic perturbation / CRISPR· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

M. M. Maurice· 2 shared A. Hedley· 1 shared A. Merenda· 1 shared A. R. Keijzer· 1 shared C. Boldrini· 1 shared C. Jensen· 1 shared C. Miller· 1 shared C. Miranti· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersCell Biology

M. M. Maurice

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

E3 ligases RNF43 and ZNRF3 display differential specificity for endocytosis of Frizzled family members

J. M. Bugter, P. van Kerkhof, E. Janssen, T. Tran Ngoc Minh, D. Iglesias van Montfort, C. Jamieson, I. Jordens, M. M. Maurice

This study shows RNF43 and ZNRF3 differentially regulate endocytosis of specific Frizzled family members through their transmembrane domains, linking these differences to cancer mutation patterns.

bioRxiv · Nov 23, 2023 · PreprintCell Biology

Intestinal LKB1 loss drives a pre-malignant program along the serrated cancer pathway

S. F. Plugge, H. Ma, J. Y. van der Vaart, J. Sprangers, F. H. M. Morsink, D. Xanthakis, C. Jamieson, K. B. W. Stroot, A. R. Keijzer, T. Margaritis, T. Candelli, R. Straver, J. de Ridder, F. C. P. Holstege, W. W. J. de Leng, , M. M. Maurice

This study shows that LKB1 loss in intestinal cells leads to a pre-malignant state linked to serrated colorectal cancer, which is amplified by loss-of-heterozygosity.

bioRxiv · Jul 17, 2023 · PreprintCancer Biology

PYCR1-dependent proline synthesis in cancer-associated fibroblasts is required for the deposition of pro-tumorigenic extracellular matrix

E. J. Kay, K. Paterson, C. Riero Domingo, D. Sumpton, H. Daebritz, S. Tardito, C. Boldrini, J. R. Hernandez-Fernaud, D. Athineos, S. Dhayade, E. Stepanova, E. Gjerga, L. J. Neilson, S. Lilla, A. Hedley, , S. Zanivan

This study identifies PYCR1-dependent proline synthesis in cancer-associated fibroblasts as critical for collagen production and tumor progression, suggesting PYCR1 as a therapeutic target to inhibit pro-tumorigenic extracellular matrix deposition.

bioRxiv · May 30, 2020 · PreprintCancer Biology

Hypoxia-Induced PIM Kinase and Laminin-Activated Integrin α6 Mediate Resistance to PI3K Inhibitors in Bone-Metastatic CRPC

R. Toth, J. Tran, M. Muldong, E. Nollet, V. Schulz, C. Jensen, L. Hazelhurst, E. Corey, D. Durden, C. Jamieson, C. Miranti, N. Warfel

The paper identifies two survival pathways in bone-metastatic CRPC that confer resistance to PI3K inhibitors and shows combined inhibition of integrin α6β1 and PIM kinase is needed to overcome this resistance.

bioRxiv · Jun 27, 2019 · PreprintCancer Biology