Max Ferretti

The paper shows that dsRNA sensing inhibits NMD, forming a negative feedback loop that limits dsRNA-mediated immune responses.

This study identifies an alternative splicing mechanism in IRF7 that generates a protein isoform with enhanced transcriptional activity, leading to increased resistance to viral infection.

This study identifies how SARS-CoV-2 evolves to counteract host interferon signaling through interactions with autophagy pathways.

This study shows that CD28 costimulation enhances alternative splicing of apoptosis-related genes, promoting T cell survival through combinatorial effects on caspase-9, Bax, and Bim.