Quirin Hammer

This study shows that NKG2A expression in iPSC-derived NK cells drives functional specialization, enhancing cytotoxicity and IFN-γ production independent of HLA-E interactions.

This paper develops a novel chimeric A/C switch receptor to target HLA-E positive cancers, showing enhanced anti-tumor activity while avoiding off-tumor toxicity.

This study investigates the effect of the SARS-CoV-2 Spike269-277 peptide YLQPRTFLL on human NK cell responses and finds it has limited influence.

This study shows that deleting adhesion ligands CD54 and CD58 on allogeneic immune cells reduces NK cell rejection without impairing their anti-tumor activity.