Emmanuel L. Gautier

This study shows that weight loss fails to reverse visceral fat fibrosis due to impaired collagen degradation, suggesting ECM clearance enhancement as a therapeutic target.

This study shows that autophagy deficiency in red pulp macrophages leads to impaired function and increased susceptibility to iron stress.

This study shows that reduced vagal signaling increases AMD risk by promoting splenic monocyte infiltration into the retina, with splenectomy reversing these effects.

The paper demonstrates that delivering FLT3L with CXCL9 and CCL5 enhances cDC1 infiltration and antitumor immunity in mice and humanized models.

The paper shows that loss of embryonically-derived Kupffer cells during hypercholesterolemia accelerates atherosclerosis by increasing liver cholesterol and reducing cholesterol regulation.

This study identifies an interaction between obesity-elicited macrophages and CD9hi progenitors that drives adipose tissue fibrosis and dysfunction in mice and humans.

The paper identifies a transcriptional signature distinguishing low- and high-risk neuroblastomas and shows that NXPH1/-NRXN signaling inhibits metastasis while promoting tumor growth.