Andrea Parmeggiani

This study investigates how septins organize membranes through self-assembly and identifies key domains involved in membrane remodeling and curvature sensing in yeast.

The paper analyzes high-resolution microscopy data to identify two distinct chromatin conformational phases in human Chr.21, showing different scaling behaviors and implications for chromatin structure.

The paper develops a biophysical model to explain the energy mechanisms behind iRBC membrane curling during malaria parasite egress, showing that lateral lipid diffusion, not viscosity, drives the process.

The paper models the ParB sliding clamp mechanism for DNA spreading and finds it cannot fully explain in vivo binding patterns and rapid assembly kinetics.

The paper shows that mechanical instabilities in the aorta drive the extrusion of haematopoietic stem/progenitor cells during embryogenesis through collective endothelial cell migration.

This study shows macrophages adapt their migratory shapes in zebrafish embryos, and this plasticity depends on Rac signalling and MMP9, which are crucial for ECM degradation and HSPC mobilisation.

The paper identifies the Nucleation & Caging model as the mechanism for ParB-parS partition complex formation, showing it is conserved across plasmids and chromosomes.