Karima Kissa

This study shows PFKFB4 has different effects on melanoma progression in two cell lines, reducing invasion in MeWo cells and tumor growth in A375P cells.

This study investigates whether cancer in zebrafish affects offspring sex ratio and survival, finding no effect on sex ratio but higher offspring survival from cancerous females.

This paper shows that melanoma progression in zebrafish is linked to nerve growth and catecholamine signaling, suggesting new therapeutic targets.

This study shows that endoglin deficiency in zebrafish causes hypoxia-driven heart failure and anemia, mirroring features of Hereditary Hemorrhagic Telangiectasia (HHT).

The paper investigates how PI3K signaling affects survival and stemness of zebrafish HSPCs during EHT, finding that both loss of Pten and PI3K inhibition induce apoptosis, while surviving cells show reduced stemness.

The paper shows that mechanical instabilities in the aorta drive the extrusion of haematopoietic stem/progenitor cells during embryogenesis through collective endothelial cell migration.

This study shows macrophages adapt their migratory shapes in zebrafish embryos, and this plasticity depends on Rac signalling and MMP9, which are crucial for ECM degradation and HSPC mobilisation.