Christopher N. LaRock

This study shows that SpeB cleavage of LL-37 does not impair CovRS signaling or reduce Spy's resistance to LL-37.

This study identifies a protease-sensing circuit in Streptococcus pyogenes linking neutrophil inflammation to virulence regulation through SpeB and Vfr interactions.

This study shows tetracycline antibiotics inhibit Pseudomonas LasB protease, reduce inflammation, and enhance neutrophil killing of bacteria in pulmonary infections.

This study identifies pentamidine as an inhibitor of streptopain, reducing Streptococcus pyogenes virulence and enhancing susceptibility to immune cells.