Author

Stephen K. Horrigan

Iterion Therapeutics (United States)ORCID 0000-0003-3055-7101Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Aundrietta D. DuncaniD· 1 shared Bai-Hua ZhangiD· 1 shared Ben Tempel· 1 shared Ciara Curran· 1 shared Colin NixoniD· 1 shared Emma PatersoniD· 1 shared Fabien ZoulimiD· 1 shared Fiona E. ChalmersiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

Aundrietta D. DuncanORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJul 16, 2026

Preclinical efficacy and safety of Tegavivint in Wnt-activated hepatocellular carcinoma

Toshiyasu Suzuki, Ciara Curran, Thomas M Drake…·Thomas Graham Bird

This study evaluates Tegavivint's efficacy and safety in Wnt-activated HCC, showing potent anti-tumour activity and safety in preclinical models.

DOI 10.64898/2026.07.14.738585

mousebulk RNA-seq

𝕏 PostBluesky

MicrobiologyJournal of VirologyPeer-reviewedNov 6, 2025

Replication-driven HBV cccDNA loss in chimeric mice with humanized livers

Bai-Hua Zhang, Yuanping Zhou, Ben Tempel…·Yong-Yuan Zhang

This study shows that replication-driven cccDNA loss occurs in HBV-infected chimeric mice with humanized livers, and blocking cccDNA replenishment pathways significantly reduces cccDNA levels.

7 citations

mouseexperimental assay

𝕏 PostBluesky