Valérie Paradis

This paper develops a self-supervised learning model to predict iCCA transcriptomic classes from histological images, achieving good to very good performance in multiple validation sets.

This study shows ZEB1 in cancer-associated fibroblasts regulates BCL2 to promote chemoresistance in cholangiocarcinoma, suggesting BCL2 inhibitors could enhance gemcitabine and cisplatin efficacy.