Author

Javier Vaquero

Centro de Investigación del CáncerORCID 0000-0002-6020-6962Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Cédric CoulouarniD· 2 shared Ester Gonzalez‐SancheziD· 2 shared Isabel FabregatiD· 2 shared Josep AmengualiD· 2 shared Aashreya RavichandraiD· 1 shared Allan PavyiD· 1 shared Ángela M. ValverdeiD· 1 shared Ania AlayiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Cédric CoulouarnORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 10, 2025

ZEB1 regulates BCL2 in cancer-associated fibroblasts to promote cholangiocarcinoma chemoresistance to gemcitabine and cisplatin

Ester Gonzalez‐Sanchez, Marie Vallette, Aashreya Ravichandra…·Javier Vaquero

This study shows ZEB1 in cancer-associated fibroblasts regulates BCL2 to promote chemoresistance in cholangiocarcinoma, suggesting BCL2 inhibitors could enhance gemcitabine and cisplatin efficacy.

DOI 10.1101/2025.09.10.675294

humanscRNA-seq

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PathologyThe Journal of PathologyPeer-reviewedJun 14, 2024

The hepatocyte Epidermal Growth Factor Receptor (EGFR) pathway regulates the cellular interactome within the liver fibrotic niche

Ester Gonzalez‐Sanchez, Javier Vaquero, Daniel Caballero‐Díaz…·Isabel Fabregat

This study shows that inhibiting EGFR in hepatocytes reduces liver fibrosis by altering immune cell populations and molecular mechanisms involved in inflammation and fibrogenesis.

12 citations

mousebulk RNA-seq

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