Jan A. Schlegel

The paper identifies IGFBP5, 6, and 7 as key regulators of CAF heterogeneity in lung cancer, showing their role in promoting tumour growth and cisplatin resistance.

VISION is an open-source software for automated multi-dimensional image analysis of cellular biophysics, enabling high throughput and correlative analysis of biophysical properties.

This study creates a neuronal in vitro model of Fabry disease to investigate small fibre neuropathy mechanisms, finding Gb3 accumulation, altered ion channel function, and mitochondrial trafficking issues.

This paper introduces a high-throughput platform for identifying host binding factors and antiviral drug targets by overcoming limitations in host plasma membrane complexity.