Author
Karlsruhe Institute of TechnologyORCID 0000-0003-3169-241XUnclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Abhik Ghosh Moulick, Sylvia Erhardt, Mariana Kozlowska
This study uses simulations to show that DNA sequence and histone variant identity differentially affect nucleosome structure and histone-DNA interactions in canonical and centromeric nucleosomes.
Abhik Ghosh Moulick, Sylvia Erhardt, Wolfgang Wenzel, Mariana Kozłowska
This study uses molecular dynamics simulations to analyze how CENP-N interacts with CENP-A nucleosomes, revealing structural changes and their impact on conformational states and protein interactions.
Tim Klingberg, Irina Wachter, Agnieszka Pancholi…·Lennart Hilbert
The paper shows that Pol II transcriptional clusters undergo a conserved condensation-dispersal sequence during stem cell differentiation across species.
Samuel Corless, Noor Pratap-Singh, Nezha S. Benabdallah…·Sylvia Erhardt
The paper identifies JQ1 as a molecular glue that targets centromeres by stabilizing BRD4-CENP-B interactions, enhancing centromere cohesion and affecting cell proliferation.
Anne Laure Pauleau, Andrea Bergner, Janko Kajtez, Sylvia Erhardt
The paper shows CAL1 links CENP-A centromere loading to mitotic timing via interaction with Zw10, a spindle assembly checkpoint protein.