Author

Marie Lycksell

Stockholm UniversityORCID 0000-0003-3271-7973Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:cryo-EM· 2 Research Focus:protein folding & dynamics· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:multiome· 1

Frequent Co-Authors

Erik R. LindahliD· 2 shared Rebecca J. HowardiD· 2 shared Chen FaniD· 1 shared Marc H. DelarueiD· 1 shared Olivia AndéniD· 1 shared Urška RovšnikiD· 1 shared Yuxuan ZhuangiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 15 mutual co-author links

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2 shared papersBiophysics

Erik R. LindahlORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintFeb 27, 2025

Structure and dynamics of a multidomain ligand-gated ion channel revealed under acidic conditions

Olivia Andén, Urška Rovšnik, Marie Lycksell…·Erik R. Lindahl

The paper uses cryo-EM, molecular dynamics, and small-angle neutron scattering to characterize an open and closed state of the bacterial ion channel DeCLIC under acidic conditions, revealing structural and dynamic mechanisms of gating.

1 citation

bacteria (other)cryo-EM

𝕏 PostBluesky

BiophysicsbioRxivPreprintFeb 24, 2025

Calcium stabilization of a flexible N-terminal domain in a pentameric ligand-gated ion channel

Chen Fan, Marie Lycksell, Yuxuan Zhuang…·Erik R. Lindahl

The paper reports cryo-EM structures of the calcium-sensitive channel DeCLIC, revealing calcium-binding sites and showing calcium stabilizes the flexible N-terminal domain.

1 citation

cryo-EMexperimental assay

𝕏 PostBluesky