Christy Susan Varghese

This study shows that 7SK-snRNP components HEXIM1 and LARP7 promote replication fork reversal and homologous recombination under transcription and replication stress, independent of BRCA1.

This study shows that HPV18 infection reprograms host transcription by altering CTCF binding and promoter-enhancer interactions, leading to repression of the tumor suppressor CADM1.

This study shows that CTCF regulates HBV cccDNA chromatin topology and nucleosomal positioning, affecting viral transcription.