Jahanara Rajwani

This study identifies microbiome-derived hydroxyphenyl propanoates (HPPs) that enhance antitumour immunity by boosting gasdermin D activity in myeloid cells, improving immune checkpoint therapy outcomes in mice and correlating with better responses in human melanoma patients.

This study identifies APOL7C as a pore-forming protein that facilitates phagosomal rupture and antigen cross-presentation by cDC1s.