Olaia Naveiras

This study identifies CD4+ cytotoxic T cells in the bone marrow that enhance granulopoiesis in aged mice, contributing to age-related diseases and showing that CCR5 inhibition can mitigate these effects.

This study investigates the role of GOLPH3 in Golgi retention and trafficking, showing its regulation by S-acylation and its impact on glycosylation and development.

The paper shows that Wnt-dependent reprogramming of bone marrow niches drives fibrosis by activating osteolineage cells and altering hematopoietic support.

This paper develops a 3D ex vivo model of bone marrow to study childhood ALL, finding increased drug resistance in certain subtypes compared to 2D models.

This study shows that Prss8 deficiency in mice causes impaired erythropoiesis and embryonic lethality due to defective terminal erythroid differentiation and vascularization.

This study shows that loss of H3K9me3 in adult mice leads to premature aging, characterized by reduced lifespan, frailty, and accelerated epigenetic aging.

MarrowDLD isolates fragile bone marrow cells without labels, achieving high purity and yield compared to FACS.

This study shows TGR5 modulates bone marrow adipose tissue and hematopoietic niche in a sex-dependent manner, affecting progenitor reconstitution and myeloid recovery.